Smallville :

After Martha contracts a strange disease and is given hours to live, Clark asks Professor Fine for help. The professor convinces Clark that Jor-El is responsible for Martha's illness and that the only way to save her is to destroy the Fortress of Solitude.

However, once the two arrive at the Fortress, Professor Fine reveals himself to be an artificial intelligence created by Kryptonians and tries to free Zod and kill Clark.